The Vomero+ 4 uses, specifically shaped heel and forefoot Nike Zoom Air units to deliver lightweight, responsive cushioning at heel strike and toe-off. Initial impact forces are also addressed by a de-coupled and articulated crash pad, which provides a smooth transition and shock absorption.

The Vomero+4 has a fill-length Cushlon midsole, which provides great responsive cushioning while being more durable than traditional compression-molded EVA. An asymmetrical arch bridge midfoot shank supports the midfoot while allowing for natural motion of a neutral foot.

The upper of the Vomero+ 4 incorporates elastich mesh panels for a dynamic mid foot fit. Extensive open mesh provides great breathability while synthetic-leather overlays offer a support. A partial bootie internal construction offers a plush feel around the foot. A Fitsole sockliner mold to the shape of the foot for improved comfort and has a soft pliable arch. The upper is finished with a strobel lasted cushlon base for additional under-foot comfort.

BRS 1000 carbon rubber is strategically placed in high wear areas for great durability. Duralon blown rubber helps reduce weight and increases responsiveness. Gender specific flex grooves deliver good flexibility and a smooth toe-off. Waffle Fill and Waffle outsole configurations provide good traction.